Teams

The Laboratory of Systems and Synthetic Biology (SSB) contributes to elucidate mechanisms underlying basic cellular processes, evolution and interactions among microbes and between microbes and their environment (including the human host). We do so in the context of entire biological systems. We translate the acquired knowledge into biotechnological, medical and environmental applications.

Our goal is deciphering the complexity of microbial metabolism, its evolutionary and biotechnological implications through a multidisciplinary approach. By assuming that the whole is greater than the sum of its parts, we aim to contribute to a better understanding of the emergent properties of microbial systems at subcellular, cellular and supracellular levels. We pursuit the rational re-design of these system properties towards novel biotechnological and medical applications.

Our research is focused on understanding the clinical and genetic basis of inherited heart disease. We use a range of approaches including human gene discovery studies, basic cellular systems, animal models of human disease, and population-based psychosocial and public health studies.Our research involves state-of-the-art approaches including whole exome sequencing, mRNA and microRNA profiling, and RNASeq. Most importantly, we have the key clinical resources, including well phenotyped individual ...

Junk/test data